What blood pressure meds are contraindicated in pregnancy?

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Some commonly prescribed antihypertensive medications should be avoided before conception and during pregnancy or are contraindicated for those times (Table 1 ). These include the majority of beta blockers, diuretics, ACE inhibitors, and angiotensin receptor antagonists.

What high blood pressure medication is safe during pregnancy?

treating pregnancy-related high blood pressure

The three most frequently prescribed medications for the initial management of high blood pressure during pregnancy are labetalol (Normodyne, Trandate), nifedipine (Procardia, Adalat), and methyldopa (Aldomet), and these are advised over all other medications.

Why is hydrochlorothiazide contraindicated in pregnancy?

Warnings about Hydrochlorothiazide during pregnancy

Additionally, jaundice, thrombocytopenia, and/or abnormal fetal or neonatal electrolytes have all been linked to the use of thiazide diuretics during pregnancy.

What blood pressure medications are contraindicated in pregnancy?

Both labetalol and methyldopa are regarded as safe for use in expecting mothers,12,13, respectively. Due to the possibility of teratogenic and fetotoxic effects, angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARB) are not advised during any trimester of pregnancy. even though this is

Can a pregnant woman take amlodipine?

Pregnancy can be treated with amlodipine. It is not believed to be harmful to the baby, despite the fact that there is not much information on its safety. Speak to your doctor if you are pregnant or planning a pregnancy. They might want to switch from amlodipine to a drug with more safety data.

Can I take lisinopril while pregnant?

pregnancies and lisinopril

Pregnancy is not advised when taking lisinopril. If taken during the second and third trimesters of pregnancy, it can have an impact on the kidney development of your unborn child. The kidneys and lungs of your baby may suffer long-term damage as a result, as well.

Is Clonidine safe in pregnancy?

Like methyldopa, clonidine hydrochloride seems to be a risk-free antihypertensive during pregnancy.

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Is losartan safe during pregnancy?

pregnancy and losartan

Pregnancy is not advised when taking losartan. Particularly if you take it during your second and third trimesters of pregnancy, it can lessen the amount of fluid surrounding your baby. This could cause long-term harm to your baby’s kidneys and lungs in addition to a host of other issues.

Can you take metoprolol when pregnant?

Does taking metoprolol while pregnant carry any risks? Studies on a small number of pregnant women who were taking metoprolol specifically found no evidence of birth defects or preterm birth. Metoprolol is a member of the beta-blocker drug class.

Which ACE inhibitor is contraindicated in pregnancy?

Angiotensin-converting enzyme (ACE) inhibitors are widely acknowledged to be contraindicated in the second and third trimesters of pregnancy due to the elevated risk of fetal renal damage. However, there is no evidence connecting first-trimester use to poor fetal outcomes.

Are beta blockers contraindicated in pregnancy?

The most popular class of drugs for treating cardiac conditions in pregnant women are beta-blockers. Despite the widespread use of this class of medications, there are few data to support their safety. Blockers pass through the placenta and may affect the fetus’s physiological development.

Why is losartan contraindicated in pregnancy?

In addition, losartan has been linked to low blood pressure, kidney disease, and kidney failure in newborns. Sometimes, these complications led to the baby’s death.

Can I take hydrochlorothiazide while pregnant?

The use of low doses (12.5 to 25 mg daily) of hydrochlorothiazide during pregnancy may minimize undesirable metabolic effects like impaired glucose tolerance and hypokalemia. Based on a few case reports, triamterene and amiloride are not teratogenic.

Can a pregnant woman take nifedipine?

Conclusions: Nifedipine in particular, as well as the dihydropyridine class of calcium channel blockers (type II calcium blockers), are safe to use during pregnancy. They have a negligible potential to be teratogenic or fetotoxic.

Is labetalol safe when pregnant?

pregnancy and labetalol

Labetalol is safe to use during pregnancy. You might be offered additional scans to make sure your baby is developing normally because labetalol can affect the baby’s growth while in the womb. Additionally, there is a slight possibility that labetalol will impact a newborn’s blood sugar levels right after birth.

Is captopril safe in pregnancy?

US: Unless there are no other options and the benefits outweigh the risks to the fetus, this medication should not be used during pregnancy.

Is propranolol safe in pregnancy?

There is no evidence to suggest that taking propranolol while pregnant is harmful. Beta blockers are a class of medications that includes propranolol. Beta blockers have not been linked to birth defects, stillbirth, or preterm delivery, according to studies.

Why is hydralazine given during pregnancy?

For severe hypertension during pregnancy, hydralazine has long been the antihypertensive of choice. Its side effects, which frequently mimic signs of deteriorating pre-eclampsia and include headache, nausea, and vomiting.

What pregnancy class is labetalol?

US FDA pregnancy category C: Although there are insufficient and well-controlled human studies and animal reproduction studies have shown a negative effect on the fetus, there may be benefits that outweigh the risks in pregnant women who use the medication.

Is atenolol safe during pregnancy?

Atenolol is a member of the beta-blocker drug class. Beta blockers have not been linked to birth defects, stillbirths, or premature birth.

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Who should not take losartan?

If you are pregnant or intend to become pregnant, let your doctor know. If you are pregnant, avoid taking losartan. If you become pregnant while taking losartan, call your doctor right away and stop the medication. When taken in the final six months of pregnancy, losartan may result in the fetus’s death or severe injury.

How is hypertension treated in pregnancy?

Preeclampsia can only be successfully treated by delivery. To prevent cerebral, cardiac, and renal complications in the mother, severe hypertension must be treated. The 2 additional types of hypertension, chronic and transient, typically progress in a less harmful manner.

What pregnancy category is losartan?

Despite possible risks, the drug may still be used during pregnancy due to potential benefits, according to the US FDA pregnancy category D, which states that there is positive evidence of a human fetal risk based on data on adverse reactions from investigational or marketing experience or human studies.

Are calcium channel blockers safe in pregnancy?

Calcium channel blockers are safe to take while nursing and pregnant.

Is Spironolactone safe during pregnancy?

Since spirolactone has anti-androgenic properties, it is frequently used to treat adult acne. Due to the possibility of the male fetus becoming feminized, the treatment is contraindicated during pregnancy (Rathnayake and Sinclair, 2010).

Are thiazide diuretics safe in pregnancy?

Pregnancy-related thiazide use has been linked to an increased risk of thrombocytopenia or jaundice in the fetus or newborn. These medications shouldn’t be used to treat hypertension in pregnant women because they don’t stop or change the progression of EPH (Edema, Proteinuria, Hypertension) gestosis (pre-eclampsia).

What is the safest beta-blocker in pregnancy?

Most experts agree that labetalol is safer than other -blockers during pregnancy, and this medication is quickly rising to the top of the list for conditions like pregnancy-related chronic hypertension.

Is diltiazem safe in pregnancy?

Diltiazem Warnings for Pregnancy

-According to some experts, use is not advised in expectant mothers or women who are not using an effective form of contraception. FDA pregnancy category in the US: not designated The risk of embryolethality, fetolethality, and/or stillbirths may be raised by this medication.

Is enalapril safe in pregnancy?

During pregnancy, enalapril-felodipine is regarded as contraindicated. When given during pregnancy, medications that directly affect the renin-angiotensin system can result in morbidity and death in fetuses and newborns. The National Institutes of Health committee advised against taking these medications while pregnant.

What is the safest blood pressure medicine?

The least risk to the mother and developing fetus is methyldopa, which lowers blood pressure by acting on the central nervous system. Beta-blockers, diuretics, and labetalol are additional potential safe alternatives.

Does nifedipine affect baby?

For your baby, nifedipine has no negative side effects. Constipation is one of the side effects that you might experience.

Does amlodipine cause birth defects?

She underwent dilatation and the removal of an embryo that was dead. As with other calcium-channel blockers, amlodipine has been reported to not be teratogenic and to be breastfeeding-compatible.

Why is nifedipine no longer used?

The dihydropyridine calcium channel blocker nifedipine was once among the most popular treatments for hypertension, but safety and tolerability issues, the development of new antihypertensive drug classes, and a growing body of evidence demonstrating the mortality benefits of other classes led to…

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Why labetalol is drug of choice in pregnancy?

Pregnancy complications brought on by high blood pressure can affect both mother and fetus. Because it has been demonstrated to effectively lower blood pressure and because it has a license for use in pregnancy, labetalol is a blood pressure medication that is advised for use during pregnancy.

Does labetalol affect baby heart rate?

neonatal bradycardia was not noticed in the drug RCTs (0/24 vs. 0/26). Whether oral methyldopa, labetalol, nifedipine, or hydralazine negatively affect fetal or neonatal heart rate and pattern cannot be determined based on the data currently available.

Is methyldopa safe in pregnancy?

Methyldopa is frequently used during pregnancy and is not likely to be harmful. When the baby is fully developed, usually after the first trimester, pregnant women taking methyldopa begin their regimen. Therefore, the baby won’t develop structural birth defects as a result.

Is Valsartan safe in pregnancy?

If you are pregnant, avoid taking valsartan. If you become pregnant while taking valsartan, call your doctor right away and stop taking the medication. When used during the final six months of pregnancy, valsartan can result in the fetus’s death or severe injury.

Why are ACEI and ARBs contraindicated in pregnancy?

Both ACE inhibitors and angiotensin II receptor blockers (ARBs) are known to harm developing kidneys in fetuses when taken during pregnancy. Their safety following first trimester exposure has been disputed due to contradictory reports in the literature.

Who should not take hydralazine?

If you are allergic to hydralazine, have coronary artery disease, or have rheumatic heart disease that affects the mitral valve, you should not use it.

Is nitroprusside contraindicated in pregnancy?

Only use of this medication during pregnancy should be clearly necessary. Category C (Nitropress) according to the US FDA; not assigned. The drug has the potential to expose the fetus to cyanide and have negative effects. A drug’s potential risk of harmful pregnancy-related outcomes cannot be determined by the available data.

Is hydralazine contraindicated in pregnancy?

Hydralazine Warnings During Pregnancy

The first two trimesters of pregnancy should be avoided, and the third trimester should not be used unless the benefits outweigh the risks to the fetus.

When should you not take labetalol?

You should not use labetalol if you are allergic to it, or if you have:

  • asthma;
  • (second or third degree) “AV block”;
  • erratic heart failure;
  • extreme hypotension;
  • You may have fainted because of your slow heartbeat.
  • if your heart is unable to adequately pump blood.

What is the problem with losartan?

Losartan is a blood pressure-lowering drug, but it occasionally lowers blood pressure too much, which can result in lightheadedness or even fainting. It may occasionally lessen blood flow to the kidneys, leading to kidney failure. Additionally, it may result in hyperkalemia, or high blood potassium (UpToDate, n.d.).

Why should you not take losartan?

Your blood can contain more potassium, which can be raised by losartan. Your risk of developing hyperkalemia is increased if you take losartan along with potassium-containing medications, potassium supplements, or potassium-fortified salt substitutes (high levels of potassium).

What’s the difference between losartan and lisinopril?

How do losartan and lisinopril function? Losartan and lisinopril essentially accomplish the same task, albeit in different ways. Losartan belongs to the ARB (angiotensin II receptor-blocker) class of medications, whereas lisinopril is an ACE (angiotensin-converting enzyme) inhibitor.